Thunberginol A

Thunberginol A
IUPAC name

3-(3,4-dihydroxyphenyl)-8-hydroxyisochromen-1-one
Identifiers
CAS number 147666-80-6
PubChem 5321948
Jmol-3D images Image 1
Properties
Molecular formula C15H10O5
Molar mass 270.23 g/mol
Exact mass 270.052823 u
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Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Thunberginol A is an isocoumarin found in Hydrangea macrophylla[1] and in its processed leaves form (Hydrangeae dulcis folium).[2][3]

References

  1. ^ Effects of phyllodulcin, hydrangenol, and their 8-O-glucosides, and Thunberginols A and F from Hydrangea macrophylla SERINGE var. thunbergii MAKINO on passive cutaneous anaphylaxis reaction in rats. Matsuda H., Shimoda H., Yamahara J. and Yoshikawa M., Biological & pharmaceutical bulletin, 1999, vol. 22, no8, pp. 870-872, INIST:1959604
  2. ^ Effects of thunberginol A contained in Hydrangeae dulcis forium on types I-IV allergies. Yamahara J, Matsuda H, Shimoda H, Wariishi N, Yagi N, Murakami N and Yoshikawa M., Nippon Yakurigaku Zasshi. 1995 May;105(5), pp. 365-379, PubMed (Article in Japanese)
  3. ^ Immunomodulatory activity of thunberginol a and related compounds isolated from hydrangeae dulcis folium on splenocyte proliferation activated by mitogens. Hisashi Matsuda, Hiroshi Shimoda, Johji Yamahara and Masayuki Yoshikawa, Bioorganic & Medicinal Chemistry Letters, Volume 8, Issue 3, 3 February 1998, pp. 215-220, doi:10.1016/S0960-894X(97)10221-9
Types of isocoumarins
Aglycones
Bergenon | Thunberginol A and B
Dihydroisocoumarins